Bioinspired interface for nanobiodevices based on phospholipid polymer chemistry.
نویسندگان
چکیده
This review paper describes novel biointerfaces for nanobiodevices. Biocompatible and non-biofouling surfaces are designed largely based on cell membrane structure, and the preparation and functioning of the bioinspired interface are evaluated and compared between living and artificial systems. A molecular assembly of polymers with a phospholipid polar group has been developed as the platform of the interface. At the surface, protein adsorption is effectively reduced and the subsequent bioreactions are suppressed. Through this platform, biomolecules with a high affinity to the specific molecules are introduced under mild conditions. The activity of the biomolecules is retained even after immobilization. This bioinspired interface is adapted to construct bionanodevices, that is, microfluidic chips and nanoparticles for capturing target molecules and cells. The interface functions well and has a very high efficiency for biorecognition. This bioinspired interface is a promising universal platform that integrates various fields of science and has useful applications.
منابع مشابه
Peptide–Polymer Conjugates for Bioinspired Compatibilization of Internal Composite Interfaces: via Specific Interactions toward Stiffer and Tougher Materials
متن کامل
Molecular motion at soft and hard interfaces: from phospholipid bilayers to polymers and lubricants.
Spatially resolved and time-resolved understanding of complex fluid situations compose a new frontier in physical chemistry. Here we draw attention to the significance of spatially resolving systems whose ensemble average differs fundamentally from the spatially resolved individual elements. We take examples from the field of fluid phospholipid bilayers, to which macromolecules adsorb; the fiel...
متن کاملSynthesis and application of chelating resins based on polyacrylonitrilediethylenetriamine for metal ions removal
Chelating resins based on polyacrylonitrile and diethylenetriamine (PAN-DTA) wereprepared through the simple reaction of polyacrylonitrile with various volume percents ofdiethylenetriamine (DTA), (25, 50, 75 and 100). The prepared resins were applied to removeheavy metal ions such as Cu(II), Zn(II) and Cd(II) from aqueous solutions. The sorptionbehaviors of the resins for these metal ions were ...
متن کاملPolymer Stabilized Lipid Membranes: Langmuir Monolayers
Polymer-tethered membranes combine fascinating structural, dynamic, and viscoelastic properties. Many important insights into these peculiar supramolecular systems can be obtained from studies on polymer-tethered monolayers. This chapter discusses recent experimental findings on polymer-tethered monolayers at the air–water interface. In particular, Langmuir monolayers which are comprised of pur...
متن کاملFabrication of an Electrochemical Sensor Based on a New Nano-ion Imprinted Polymer for Highly Selective and Sensitive Determination of Molybdate
In this work a new chemically modified carbon paste electrode was constructed for accurate, simple, sensitive and selective determination of molybdenum (VI) ions. The results of modified electrode by an ion imprinted polymer were compared with those obtained with carbon paste electrode. The results showed the stripping peak currents had a dramatic increase at the modified electrode. Under the o...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of the Royal Society, Interface
دوره 6 Suppl 3 شماره
صفحات -
تاریخ انتشار 2009